
DymatizeISO100 Hydrolyzed Whey Protein Isolate
Hydrolyzed whey isolate: 25 g protein, 1 g sugar or less and cult-favorite flavors
By FitnessReviews Editors6 sourcesMore from Dymatize
Ranked #2 in The Best Protein Powders of 2026FR Score
Excellent
Built from 5 independent video reviews, label & spec analysis, and value. How we score
An editorial research score. We have not verified hands-on testing by our editors for this product.
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- Protein per serving
- 25 g
- Calories per serving
- 120 or less
- Sugar per serving
- 1 g or less
- BCAAs per serving
- 5.5 g (2.6 g leucine)
The verdict
ISO100 is the go-to isolate for lean macros and easy digestion, with 25 g of protein, 120 calories or less and 1 g of sugar or less per scoop, all from whey isolate. Reviewers rave about flavors like Fruity Pebbles and Gourmet Chocolate. The trade-off is a higher price per serving than whey blends.
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Score breakdown
What we like
- 100% of protein from whey isolate, partly hydrolyzed
- 1 g of sugar or less and 120 calories or less per 25 g protein scoop
- Standout flavors, including Pebbles cereal collaborations
- Banned-substance tested; retailers list Informed Choice certification
- Very fine powder that mixes quickly in water
Watch out for
- Pricier per serving than whey blends
- Flavored versions use sucralose and soy lecithin
- Some flavors taste very sweet
Video review catalog
5 real reviews of the ISO100 Hydrolyzed Whey Protein Isolate
3 on YouTube 2 on TikTok· Independent creators, picked for depth and honesty.1 recommend
Short-form reviews
Full review
Overview
Dymatize ISO100 uses hydrolyzed whey protein isolate: whey filtered to strip out most lactose, fat and carbs, then partially broken into smaller peptides for fast digestion. Per scoop you get 25 g of protein, 5.5 g of BCAAs including 2.6 g of leucine, 120 calories or less and 1 g of sugar or less. Dymatize labels it banned-substance tested, and major retailers list it as Informed Choice certified. Flavored versions are sweetened with sucralose and contain soy lecithin.
What reviewers say
The consensus from dietitians, coaches and taste-testers is that this is one of the best-tasting isolates you can buy. Fruity Pebbles, Cocoa Pebbles and Gourmet Chocolate earn repeat praise, although a few TikTok reviewers find Fruity Pebbles very sweet. The powder is extremely fine and mixes into a thin, slightly frothy shake in water. Garage Gym Reviews calls it delicious and recommends it to anyone prioritizing protein with minimal carbs or fat, while coach Dr. Marc Morris devotes part of his review to who should skip it, since you are paying extra for the hydrolyzed isolate.
Who it's for
Lifters in a cutting phase who want maximum protein per calorie, people who feel bloated on concentrate-heavy blends, and tested athletes who want a certified product with a deep flavor menu. It also suits anyone who prefers a light, juice-thin shake after training rather than a thick, milkshake-style drink.
Bottom line
If you want an isolate that genuinely tastes good, ISO100 is the safe bet. At about $1.55 per serving for the 5 lb tub, it costs more than blends, but you get cleaner macros and very low lactose for the money.
Specs & details
- Protein per serving
- 25 g
- Calories per serving
- 120 or less
- Sugar per serving
- 1 g or less
- BCAAs per serving
- 5.5 g (2.6 g leucine)
- Protein source
- Hydrolyzed whey protein isolate and whey protein isolate
- Servings
- 71 per 5 lb tub (Gourmet Chocolate)
- Sweetener
- Sucralose
- Allergens
- Milk, soy (soy lecithin)
- Third-party testing
- Banned-substance tested (Informed Choice per retailer listings)
Frequently asked questions
What does hydrolyzed mean on ISO100?
Is ISO100 a good choice if dairy upsets my stomach?
Is Dymatize ISO100 third-party tested?
This review is for information only and isn’t medical advice. Supplements aren’t reviewed by the FDA before sale — check with a doctor or pharmacist before starting one, especially if you’re pregnant, take medication or have a health condition. Health disclaimer
Compare
ISO100 Hydrolyzed Whey Protein Isolate vs. the alternatives
![]() | ![]() | ![]() | ![]() | |
|---|---|---|---|---|
| FR Score | 8.9 out of 10FR ScoreExcellent | 9.1 out of 10FR ScoreExceptional | 8.8 out of 10FR ScoreExcellent | 8.2 out of 10FR ScoreGreat |
| Best for | Best Whey Isolate | Best Overall | Best Clean Label | Best Budget |
| Typical price | See retailer | ~$131.99 | ~$64.99 | See retailer |
| Video reviews | 5 | 5 | 4 | 4 |
| Where to buy | Amazon · TikTok Shop · Brand | Amazon · TikTok Shop · Brand | Amazon · TikTok Shop · Brand | Amazon · TikTok Shop · Brand |
Head-to-head comparisons
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